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Human Prostate Cancer Peripheral Blood Mononuclear Cells

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Included Diagnoses: Adenocarcinoma (including all subtypes) and Squamous Cell Carcinoma (including all subtypes), Neuroendocrine tumors of the prostate, Carcinoma of the prostate.
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Home | Primary Cells | Human Primary Cells | PBMCs | Human Prostate Cancer Peripheral Blood Mononuclear Cells
Species

Human
Cat.No

ABC-TC4338
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Primary Cells
Size/Quantity

1 vial
Cell Type

Mononuclear Cell
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Peripheral Blood
Disease

Prostate Cancer
Storage

Liquid Nitrogen
Product Type

Diseased Human Peripheral Blood Mononuclear Cells

Description

Human Prostate Cancer Peripheral Blood Mononuclear Cells are immune cells isolated from the peripheral blood of prostate cancer patients, primarily comprising lymphocytes (T cells, B cells, NK cells) and monocytes. These cells play critical roles in antitumor immune responses, including antigen presentation (monocytes/macrophages), cytotoxic activity (NK cells/CD8+ T cells), and antibody production (B cells). In prostate cancer, PBMCs often exhibit altered immune function, such as expansion of immunosuppressive regulatory T cell (Treg) or impaired cytotoxic T cell responses, which contribute to tumor immune evasion.

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Citation

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Application

  • Human Prostate Cancer Peripheral Blood Mononuclear Cells can be used to study immune cell dysfunction, such as T-cell exhaustion or regulatory T-cell (Treg) expansion, which contribute to immune evasion in prostate cancer. They can also serve as a platform for developing immunotherapies, including immune checkpoint inhibitor studies, adoptive cell therapies (e.g., CAR-T cells), and cancer vaccine development.

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