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Primary Cells

Human Pulmonary Artery Endothelial Cells

  • For research use only

Cat No.

ABC-TC4046
Product Type

Vascular Cells
Cell Type

Endothelial
Species

Human
Growth Conditions

37 ℃, 5% CO2
Disease

Normal
Storage

Liquid Nitrogen

Pulmonary Artery Endothelial Cells ,Primary pulmonary artery endothelial cells from healthy donors, idea for vascular biology and cardiovascular studies.

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  • Human Pulmonary Artery Endothelial Cells
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Description

Human Pulmonary Artery Endothelial Cells (HPAEC) are primary endothelial cells isolated from the intimal layer of pulmonary arteries obtained from healthy adult donors. Cells are collected under sterile conditions. HPAEC display typical cobblestone morphology and form adherent monolayers. Cryopreserved at early passage, they retain phenotypic stability and functional responsiveness. These cells are essential regulators of pulmonary vascular tone, leukocyte trafficking, and endothelial barrier function, especially under hypoxic or inflammatory conditions. HPAEC express endothelial-specific markers including CD31, VE-cadherin, and von Willebrand factor. Each lot undergoes rigorous screening and isolation procedures and is tested to ensure it is free from contamination by HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
Product Code

Human Pulmonary Artery Endothelial Cells, Pulmonary Arterial Endothelial Cells, HPAECs, Lung Artery Endothelial Cells
Species

Human
Cat.No

ABC-TC4046
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Endothelial
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Vascular Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • HPAEC are widely used in pulmonary and vascular research to study endothelial function, barrier regulation, and hypoxia-induced remodeling. They provide a robust in vitro model for investigating pulmonary hypertension, acute lung injury, and vascular inflammation. HPAEC also support drug discovery efforts aimed at modulating leukocyte adhesion, permeability, and vasoreactivity, making them valuable tools in both mechanistic studies and therapeutic screening for cardiopulmonary diseases.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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