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Primary Cells

Human Rectal Smooth Muscle Cells

  • For research use only

Cat No.

ABC-TC3780
Product Type

Intestinal Cells
Cell Type

Smooth Muscle Cell
Species

Human
Growth Conditions

37 ℃, 5% CO2
Source Organ

Rectal
Disease

Normal
Storage

Liquid Nitrogen

Human Rectal Smooth Muscle Cells from AcceGen Research Laboratories are isolated from the human rectum.

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  • Human Rectal Smooth Muscle Cells
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Home | Primary Cells | Human Primary Cells | Digestive System Primary Cells | Human Rectal Smooth Muscle Cells

Description

Human Rectal Smooth Muscle Cells (HRecSMCs) are primary cells derived from the muscularis propria layer of healthy human rectal tissue. These adherent, spindle-shaped cells display the characteristic "hill-and-valley" growth pattern typical of visceral smooth muscle. Isolated under sterile conditions and cryopreserved at early passage, HRecSMCs retain their contractile phenotype and express key smooth muscle markers, including α-smooth muscle actin (α-SMA), smooth muscle myosin heavy chain (SM-MHC), and h-caldesmon. These cells respond to neurotransmitters and mechanical stretch, modeling physiological contraction and relaxation dynamics of the rectal wall. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
Product Code

HRSMC
Species

Human
Cat.No

ABC-TC3780
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Smooth Muscle Cell
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Rectal
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Intestinal Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Human Rectal Smooth Muscle Cells (HRecSMCs), also known as primary human rectum SMCs or human lower intestinal smooth muscle, are widely used to investigate rectal motility, enteric neurotransmission, and smooth muscle remodeling in gastrointestinal (GI) disorders such as irritable bowel syndrome (IBS), chronic constipation, and inflammatory bowel disease (IBD). They are also valuable for evaluating prokinetic agents, anti-fibrotic therapies, and modeling smooth muscle–immune interactions in the GI tract. In tissue engineering, HRecSMCs support the development of bioengineered intestinal models and regenerative medicine approaches targeting smooth muscle repair.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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