| Product Code |
HSF
|
| Species |
Human
|
| Cat.No |
ABC-TC3818
|
| Quality Control |
All cells test negative for mycoplasma, bacteria, yeast, and fungi.
|
| Product Category |
Primary Cells |
| Size/Quantity |
1 vial
|
| Cell Type |
Fibroblast
|
| Shipping Info |
Dry Ice
|
| Growth Conditions |
37 ℃, 5% CO2
|
| Source Organ |
Spleen
|
| Disease |
Normal
|
| Biosafety Level |
1
|
| Storage |
Liquid Nitrogen
|
| Product Type |
Spleen Cells
|
Description
Human Splenic Fibroblasts are primary cells isolated from the spleen of healthy human donors, a key secondary lymphoid organ essential for immune regulation and hematopoiesis. Derived specifically from the white pulp, they exhibit spindle-shaped fibroblast-like morphology and adherent growth in vitro. These fibroblasts include T-zone reticular cells (CCL21⁺), follicular dendritic cells (CXCL13⁺, CR1/2⁺), and marginal reticular cells (CXCL13⁺, MAdCAM1⁺, RANKL⁺). Functionally, they regulate lymphocyte migration, antigen presentation, and splenic architecture. Their immunomodulatory nature and in vitro adaptability make them valuable in immunology, vascular biology, and stromal research. They express PDGFRβ, CD90, and vimentin, confirmed by flow cytometry and immunocytochemistry. These non-immortalized cells cannot be passaged indefinitely, preserving native function. All samples are negative for HIV-1, HIV-2, HBV, HCV, and mycoplasma to ensure biosafety.
