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Primary Cells

Human Thyroid Fibroblasts

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Fibroblasts are mesenchymal cells derived from the embryonic mesoderm. They have been extensively used for a wide range of cellular and molecular studies. This is mainly because they are one of easiest types of cells to grow in culture, and their durability makes them amenable to a wide variety of manipulations ranging from studies employing […]
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Home | Primary Cells | Human Primary Cells | Endocrine System Primary Cells | Human Thyroid Fibroblasts
Product Code

HThF
Species

Human
Cat.No

ABC-TC3832
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Primary Cells
Size/Quantity

1 vial
Cell Type

Fibroblast
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Thyroid
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Thyroid Cells
Key Features

-Backed by AcceGen advanced technology
-Cryopreserved for highest viability and plating efficiency
-Quality-tested for accurate results
-Expert teams to provide timely support and assist best experimental outcomes

Description

Fibroblasts were first described in 19th century and can be found in many different sites of the human body with a substantial topographic diversity. Thyroid fibroblasts are found in the capsule of the thyroid gland, an endocrine organ responsible for hormone homeostasis and iodine concentration. Fibroblasts in thyroid gland have been suggested to possess several characteristic attributes that associated with thyroid dysfunction. With a unique ganglioside expression profile, thyroid hormone fibroblasts involve in the crosstalk with immunocompetent cells, suggesting a potential role in the inflammatory responses of thyroid gland. The abnormal accumulation of hyaluronan that sourced from thyroid fibroblasts can also contribute greatly to the thyroid-associated disease such as hypothyroidism and Graves’ disease.
Why choose Human Thyroid Fibroblasts from AcceGen?
AcceGen Human thyroid fibroblasts are isolated from human thyroid tissue. Cells are cryopreserved immediately after isolation with each vial contains at least 5×10^5 cells in 1 ml volume. HThF are characterized by their spindle morphology and immunofluorescence with antibodies specific to fibronectin. All cell lots are tested negative for HIV-1, HBV, HCV and other pathogens.

AcceGen Frozen Cells & Cell Lines 1 vial
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Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

  • For research use only

  • Fibroblasts are one of the most commonly used cell types for in vitro studies and manipulations. Thyroid gland fibroblasts provide an ideal model for studying the physiology and pathophysiology associated with fibroblasts in thyroid. The specificity of thyroid fibroblasts in mesenchymal–epithelial cell interactions, surface protein expression can be used for studies on the thyroid-associated disease such as papillary thyroid carcinoma and thyroid-associated ophthalmopathy and dermopathy.

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