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Primary Cells

Human Thyroid Fibroblasts

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Fibroblasts are mesenchymal cells derived from the embryonic mesoderm. They have been extensively used for a wide range of cellular and molecular studies. This is mainly because they are one of easiest types of cells to grow in culture, and their durability makes them amenable to a wide variety of manipulations ranging from studies employing […]
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Product Code

HThF

Species

Human

Cat.No

ABC-TC3832

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Primary Cells
Size/Quantity

1 vial

Cell Type

Fibroblast

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Thyroid

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Thyroid Cells

Key Features

-Backed by AcceGen advanced technology
-Cryopreserved for highest viability and plating efficiency
-Quality-tested for accurate results
-Expert teams to provide timely support and assist best experimental outcomes

Description

Human Thyroid Fibroblasts are derived from normal human thyroid tissue. They are derived from normal, non-diseased human thyroid tissue.The cells are fibroblast-like in morphology, appearing as long spindles, and grow in an adherent manner. Human thyroid fibroblasts secrete and synthesize extracellular matrix components critical for maintaining thyroid tissue structure and function. In addition, they play a central role in wound healing and can participate in thyroid tissue repair in response to injury and inflammatory signals.They express fibroblast markers such as vimentin and fibroblast-specific protein 1 (FSP1), detectable by immunocytochemistry or flow cytometry. Many diseases, such as thyroid fibrosis, are associated with abnormal activity of fibroblasts, and their abnormalities may lead to damage to the structure and function of thyroid tissue.

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Citation

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Application

  • Human Thyroid Fibroblasts can be used to study the pathogenesis of thyroid-related diseases, such as microenvironmental regulation of thyroid fibrosis, Hashimoto’s thyroiditis, and thyroid cancer. These cells can also be used to explore the interaction between fibroblasts and thyroid follicular cells, revealing the molecular pathways of immune cell infiltration and fibrosis development.

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High Viability
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To support a consistent result
Customization Options
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