Transfected Stable Cell Lines

Human TNK1_AAA BAF3 Cell Line

  • For research use only

Cat No.

ABC-X0064C

Product Type

Overexpression Stable Cell Lines

Cell Type

Lymphocytes

Species

Human

Host Cell

BAF3

Source Organ

Lymphatic

Disease

Normal

Storage

Liquid Nitrogen

TNK1-AAA BAF3 Cell Line is optimized for studying tyrosine kinase activity modulation and screening therapeutic strategies targeting TNK1 signaling.

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Description

The Human TNK1_AAA BAF3 Cell Line is a genetically engineered model derived from the murine pro-B cell line BAF3 based on customers’ requirement. This overexpression cell line is generated by stable integration of exogenous human TNK1_AAA fusion gene into BAF3 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
TNK1_AAA represents a constitutively active form of TNK1 (tyrosine kinase non-receptor 1) modified to include gain-of-function mutations. TNK1 is a cytoplasmic tyrosine kinase implicated in innate immunity and tumor suppression. Mutant forms may drive pro-survival signaling through NF-κB and STAT pathways. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human

Cat.No

ABC-X0064C

Product Category

Transfected Stable Cell Lines

Size/Quantity

1 vial

Cell Type

Lymphocytes

Growth Mode

Suspension

Shipping Info

Dry Ice

Growth Conditions

37 °C, 5% CO2

Source Organ

Lymphatic

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Overexpression Stable Cell Lines

Host Cell

BAF3

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • The Human TNK1_AAA BAF3 Cell Line enables functional studies on TNK1-mediated oncogenic transformation and signaling dynamics. It supports discovery of TNK1-targeted compounds and understanding of inflammatory and hematologic disease pathogenesis.

Inquiring Human TNK1_AAA BAF3 Cell Line

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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