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Human TNK1_AAA BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human TNK1_AAA BAF3 Cell Line
Species

Human
Cat.No

ABC-X0064C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

The Human TNK1_AAA BAF3 Cell Line is a genetically engineered model derived from the murine pro-B cell line BAF3 based on customers’ requirement. This overexpression cell line is generated by stable integration of exogenous human TNK1_AAA fusion gene into BAF3 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
TNK1_AAA represents a constitutively active form of TNK1 (tyrosine kinase non-receptor 1) modified to include gain-of-function mutations. TNK1 is a cytoplasmic tyrosine kinase implicated in innate immunity and tumor suppression. Mutant forms may drive pro-survival signaling through NF-κB and STAT pathways. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The Human TNK1_AAA BAF3 Cell Line enables functional studies on TNK1-mediated oncogenic transformation and signaling dynamics. It supports discovery of TNK1-targeted compounds and understanding of inflammatory and hematologic disease pathogenesis.

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