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Transfected Stable Cell Lines

HVEM Reporter Jurkat Cell Line

  • For research use only

Cat No.

ABC-RC113F
Product Type

Reporter Stable Cell Lines
Cell Type

T Lymphoblast
Species

Human
Host Cell

Jurkat
Source Organ

Blood
Disease

Acute T Cell Leukemia
Storage

Liquid Nitrogen

HVEM Reporter Jurkat Cell Line provides a T-cell model to investigate immune checkpoint signaling, TNFR superfamily interactions, and drug screening.

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  • HVEM Reporter Jurkat Cell Line
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Home | Transfected Stable Cell Lines | Reporter Stable Cell Lines | HVEM Reporter Jurkat Cell Line

Description

HVEM (TNFRSF14) is a member of the tumor necrosis factor (TNF) receptor family, a transmembrane protein characterized by multiple cysteine-rich domains (CRD) in its structure. HVEM is widely expressed on various immune cells, including dendritic cells, naïve T cells, B cells, NK cells, monocytes, and neutrophils.HVEM has multiple ligands such as BTLA, CD160, LIGHT, and lymphotoxin-α (LTα). By interacting with these ligands, HVEM activates pro-inflammatory signaling pathways.The HVEM Reporter Jurkat Cell Line is a luciferase reporter cell line constructed based on the mechanism of action. When BTLA binds to HVEM, it activates downstream signaling pathways, leading to the expression of luciferase, a process that can be blocked by antibodies with a blocking effect. Luciferase readings indicate the activation effect of the signaling pathway and can be used to evaluate the in vitro effects of HVEM agonists, BTLA, HVEM antagonists, and other drugs.

Species

Human
Cat.No

ABC-RC113F
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

T Lymphoblast
Growth Mode

Suspension
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Blood
Disease

Acute T Cell Leukemia
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Reporter Stable Cell Lines
Host Cell

Jurkat

Application

  • For research use only

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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