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Immortalized Cell Lines

Immortalized Human Endometrial Epithelial Cells

  • For research use only

Cat No.

ABC-H0045X
Product Type

Immortalized Cell Line
Cell Type

Epithelial
Species

Human
Growth Conditions

37 ℃, 5% CO2
Source Organ

Endometrium
Disease

Normal
Storage

Liquid Nitrogen

Immortalized Human Endometrial Epithelial Cells for modeling endometrial biology, hormone response, and epithelial cell behavior in reproductive studies.

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  • Immortalized Human Endometrial Epithelial Cells
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Home | Immortalized Cell Lines | Immortalized Human Endometrial Epithelial Cells

Description

Immortalized Human Endometrial Epithelial Cells are a immortalized human epithelial cell line derived from the endometrial lining of a healthy adult female donor, immortalized with SV40 large T antigen. These endometrial cells display typical epithelial characteristics with a cobblestone-like morphology and adherent growth pattern in culture. They express endometrial markers such as cytokeratin 18 (KRT18), epithelial cell adhesion molecule (EpCAM), a nd E-cadherin (CDH1). Under air-liquid interface (ALI) conditions, they form spheroids and differentiate into stromal-like cells. They respond to estrogen and progesterone signaling, mirroring the hormonal responsiveness of native endometrial tissue. This cell line provides a stable, non-tumorigenic in vitro model for studying human reproductive biology, endometrial function, embryo implantation, inflammation, and hormone-driven pathologies such as endometriosis and endometrial cancer, offering a non-malignant epithelial comparator to cancer-derived models such as Ishikawa cell line.

Species

Human
Cat.No

ABC-H0045X
Product Category

Immortalized Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Endometrium
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Immortalized Cell Line
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Immortalized Human Endometrial Epithelial Cells are ideal for studying endometrial physiology, hormonal signaling, embryo implantation, and reproductive toxicology. They also serve as a platform for investigating endometrial disease mechanisms, including inflammation, fibrosis, and neoplastic transformation under controlled conditions. In addition, these cells offer a valuable tool to recapitulate the pathogenesis of various endometrium-related carcinomas, such as ovarian clear cell carcinoma, uterine endometrioid carcinoma, and ovarian endometrioid carcinoma, by studying the interactions between normal cells and their malignant counterparts.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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