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Species | Human |
Cat.No | ABC-H0041X |
Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Product Category | Immortalized Cell Lines |
Size/Quantity | 1 vial |
Cell Type | Fibroblast |
Shipping Info | Dry Ice |
Growth Conditions | 37 ℃, 5% CO2 |
Source Organ | Intestine |
Disease | Normal |
Biosafety Level | 1 |
Storage | Liquid Nitrogen |
Product Type | Immortalized Cell Line |
Immortalized Human Intestine Fibroblasts are derived from primary human intestinal fibroblasts that have been immortalized using the SV40 large T antigen. Following the primary culture, these cells are cryopreserved. Immortalized Human Intestine Fibroblasts play an important role in intestinal barrier, tissue repair, and intestinal tissue integrity maintenance, serving as critical tools for studying epithelial-mesenchymal interactions. In vitro, these cells should be avoided repeated freeze-thaw cycles during the culture process.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
Immortalized Human Intestine Fibroblasts provide a physiologically relevant in vitro model for studying intestinal fibroblast biology and the pathogenesis of gastrointestinal diseases. They support research into gut tissue architecture, extracellular matrix remodeling, and epithelial-mesenchymal crosstalk, and involve in studying the small intestine physiology and also the mechanisms of carcinogenesis. These cells are also employed in high-throughput drug screening platforms, accelerating the discovery of therapies for inflammatory bowel diseases (IBD), intestinal fibrosis, and colorectal cancer stromal interactions.