For research use only
| Cat No. | ABC-TC0454 |
| Product Type | Human Melanoma Cell Lines |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Disease | Melanoma |
| Product Code | ISTMEL1 |
Species: human, Caucasian male adult; Tissue: skin; Tumor: melanoma
IST-MEL1 is a human cutaneous melanoma tumor cell line originally derived from in situ skin tumor tissue of a Caucasian adult male patient with malignant melanoma of the skin. It exhibits an epithelial-like morphology and grows as adherent monolayers in standard culture conditions. Genomic analyses show that it is microsatellite stable (MSS) and harbors a clinically relevant BRAF p.Val600Glu (V600E) mutation, a driver mutation that activates MAPK signaling in melanoma biology, along with TP53 alterations associated with tumor progression. As a malignant melanoma model, it provides a platform to study tumor cell proliferation and oncogenic signaling in skin cancer. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | ISTMEL1 |
| Species | Human |
| Cat.No | ABC-TC0454 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Disease | Melanoma |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Melanoma Cell Lines |
IST-MEL1 cell line is used as an in vitro model of human cutaneous melanoma for investigating tumor cell proliferation, BRAF-driven signaling pathways, and drug response mechanisms. Their characterized genomic profile supports studies in targeted therapy evaluation and pharmacogenomic profiling relevant to melanoma research.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
