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Transfected Stable Cell Lines

KLN205/NFκB Reporter (Luc) Stable Cell Line

  • For research use only

Cat No.

ABC-RC010Y
Product Type

Reporter Stable Cell Lines
Cell Type

Epithelial
Species

Mouse
Host Cell

KLN205
Source Organ

Lung
Disease

Squamous Cell Carcinoma
Storage

Liquid Nitrogen

KLN205/NFκB Reporter (Luc) Stable Cell Line enables high-sensitivity bioluminescent monitoring of NFκB signaling in cancer inflammation research.

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  • KLN205/NFκB Reporter (Luc) Stable Cell Line
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Home | Transfected Stable Cell Lines | KLN205/NFκB Reporter (Luc) Stable Cell Line

Description

KLN205/NFκB Reporter (Luc) Stable Cell Line is a bioluminescent reporter model engineered from murine lung squamous carcinoma KLN205 cells, featuring stable integration of a luciferase gene under NFκB-responsive promoter elements. This engineered cell line maintains the epithelial morphology and tumorigenic features of parental KLN205 cells while enabling quantitative, real-time monitoring of NFκB signaling activity. The reporter responds sensitively to pro-inflammatory cytokines such as TNF-α and IL-1β, pathogen-associated molecular patterns, and pharmacological modulators. Applications include inflammation–cancer crosstalk studies, tumor microenvironment research, high-throughput screening of NFκB modulators, and evaluation of drug resistance mechanisms. All cells are rigorously tested and confirmed negative for mycoplasma, fungi, yeast, and bacteria.

Species

Mouse
Cat.No

ABC-RC010Y
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Lung
Disease

Squamous Cell Carcinoma
Biosafety Level

2
Storage

Liquid Nitrogen
Product Type

Reporter Stable Cell Lines
Host Cell

KLN205
Gene Info

Luciferase (NFκB-responsive reporter)
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • The KLN205/NFκB Reporter (Luc) Stable Cell Line provides a highly sensitive luciferase-based system for monitoring NFκB signaling in real time. It enables quantitative assessment of inflammatory responses, innate immune signaling, and drug-induced NFκB activation, making it an excellent platform for high-throughput inhibitor screening and mechanistic studies in lung squamous carcinoma research.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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