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Transfected Stable Cell Lines

KLN205 SMAD/TGF β Reporter (Luc) Stable Cell Line

  • For research use only

Cat No.

ABC-RC008Y
Product Type

Reporter Stable Cell Lines
Cell Type

Epithelial
Species

Mouse
Host Cell

KLN205
Source Organ

Lung
Disease

Squamous Cell Carcinoma
Storage

Liquid Nitrogen

KLN205 SMAD/TGF β Reporter (Luc) Stable Cell Line by AcceGen enables quantitative bioluminescent monitoring of SMAD/TGF β signaling in cancer research.

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  • KLN205 SMAD/TGF β Reporter (Luc) Stable Cell Line
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Home | Transfected Stable Cell Lines | KLN205 SMAD/TGF β Reporter (Luc) Stable Cell Line

Description

KLN205 SMAD/TGF β Reporter (Luc) Stable Cell Line is a bioluminescent reporter model engineered from murine lung squamous carcinoma KLN205 cells, featuring stable integration of a luciferase gene driven by SMAD-responsive promoter elements. This system allows sensitive, quantitative monitoring of TGF β pathway activation through luciferase expression, while preserving the epithelial morphology and tumorigenic features of parental KLN205 cells. The luciferase reporter provides a robust platform for tracking SMAD/TGF β signaling dynamics in response to ligands such as TGF β1 and BMPs, or pharmacological modulators. Applications include studies of epithelial–mesenchymal transition (EMT), tumor–microenvironment interactions, high-throughput drug screening, and preclinical evaluation of TGF β-targeting therapeutics. All cells are rigorously quality controlled and confirmed negative for mycoplasma, fungi, yeast, and bacteria.

Species

Mouse
Cat.No

ABC-RC008Y
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Lung
Disease

Squamous Cell Carcinoma
Biosafety Level

2
Storage

Liquid Nitrogen
Product Type

Reporter Stable Cell Lines
Host Cell

KLN205
Gene Info

Luciferase (SMAD / TGF β-responsive reporter)
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • The KLN205 SMAD/TGF β Reporter (Luc) Stable Cell Line is designed for sensitive monitoring of TGF β signaling through luciferase expression. This bioluminescent system enables quantitative, real-time assessment of SMAD-mediated transcriptional activity in response to TGF β stimulation, supporting studies on TGF β’s dual role in tumor suppression and progression. It is particularly useful for drug screening, EMT research, and tumor–microenvironment analysis in lung squamous carcinoma models.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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