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Product Code | LN 319; LN319 |
Species | Human |
Cat.No | ABC-TC499S |
Product Category | Tumor Cell Lines |
Size/Quantity | 1 vial |
Cell Type | Epithelial |
Shipping Info | Dry Ice |
Growth Conditions | 37 ℃, 5% CO2 |
Source Organ | Brain |
Storage | Liquid Nitrogen |
Product Type | Human Nerve Tumors Cell Lines |
LN-319 is a human brain epithelial carcinoma cell line that was originally isolated from a left malignant glioma of a 69-year-old Caucasian male with anaplastic astrocytoma grade III. LN-319 exhibits epithelial-like morphology and adherent culture properties.
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LN-319 cells model brain epithelial cancer mechanisms, progression, and therapeutic responses (including targeted therapies, chemotherapy, and immunotherapies). They enable genomic/proteomic studies to identify genetic markers and signaling pathways, drug screening for anti-cancer compound efficacy, and immunotherapy research exploring immune system interactions. Additionally, they facilitate biomarker discovery for early detection and prognosis, alongside cell biology investigations of cell cycle regulation, apoptosis, and signal transduction pathways.