For research use only
| Cat No. | ABC-TC0599 |
| Product Type | Human Prostate Cancer Cell Lines |
| Cell Type | Epithelial |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Product Code | LNCaP-Clone-FGC; LNCaP.FGC; LNCaP-FGC; LNCaP FGC; LNCAPCLONEFGC |
Discover how LNCaP, clone FGC supports prostate cancer modeling and androgen-responsive assays for drug screening and hormone receptor analysis.
LNCaP clone FGC is a human prostate adenocarcinoma cell line derived from a lymph node metastasis of a 50-year-old Caucasian male patient. These cells exhibit an epithelial morphology characterized by polygonal shape and tight junctions. LNCaP cells are androgen-sensitive, expressing androgen receptor (AR) and prostate-specific antigen (PSA), making them a widely used model for studying prostate cancer progression and hormone responsiveness. This cell line harbors a mutation in the androgen receptor gene (T877A), affecting ligand binding and activity. LNCaP cells also display a near-diploid karyotype with chromosomal abnormalities typical of prostate cancer. They are tumorigenic in immunodeficient mice and useful for investigating mechanisms of androgen-dependent growth and resistance.
| Product Code | LNCaP-Clone-FGC; LNCaP.FGC; LNCaP-FGC; LNCaP FGC; LNCAPCLONEFGC |
| Species | Human |
| Cat.No | ABC-TC0599 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Prostate Cancer Cell Lines |
LNCaP clone FGC cells are extensively used to study prostate cancer biology, particularly androgen receptor signaling, tumor growth, and mechanisms of castration resistance. They serve as a key in vitro model for testing anti-androgen drugs and investigating molecular pathways underlying hormone sensitivity and resistance. The cell line supports research into tumor metastasis, gene regulation, and therapeutic responses.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
