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PC-3 | ||||
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| Product Name | PC-3 | |||
| Price | Get Quote | |||
| Product Code | PC3; PC.3 | |||
| Cat.No | ABC-TC0903 | Species | Human | |
| Size/Quantity | 1 vial | Biosafety Level | 1 | |
| Shipping Info | Dry Ice | Storage | Liquid Nitrogen | |
| Description | PC-3 is a cell line derived from a bone metastasis of a grade IV prostatic adenocarcinoma in a 62-year-old White male, known for its high metastatic potential. Notably, PC-3 cells are androgen-independent, unresponsive to androgens, glucocorticoids, or fibroblast growth factors, and instead, they are influenced by epidermal growth factors. Unlike other prostate cancer cell models, they exhibit low testosterone-5-alpha reductase and acidic phosphatase activity and do not express prostate-specific antigen (PSA). PC-3 cells are characterized by their small-cell neoendocrine carcinoma phenotype and exhibit distinctive morphological and molecular features. In terms of size, PC-3 cells measure approximately 15.1 to 16.6 micrometers in diameter.
Why choose PC-3 from AcceGen? PC-3 cells exhibit high viability and quality, ensuring robust experimental outcomes. They are maintained under sterile conditions, rigorously tested to be negative for bacteria, fungi, and mycoplasma contamination, and their identity is confirmed through STR analysis, emphasizing their reliability and adherence to stringent quality control standards. | |||
| Source Organ | Prostate | |||
| Recommended Medium And Supplement | RPMI 1640 + 10% FBS | |||
| Citation Guide | When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID). | |||
| Application | FOR RESEARCH USE ONLY The PC-3 cell line is a crucial asset in prostate cancer research, allowing scientists to delve into biochemical alterations and assess how advanced prostate cancer cells respond to various chemotherapeutic agents. Beyond this, PC-3 cells are commonly employed in studies focusing on viral infections | |||
| Growth Conditions | 37 ℃, 5% CO2 | |||
| Cell Type | Epithelial | |||
| Growth Mode | Adherent | |||
| Product Type | Human Prostate Cancer Cell Lines | |||
| Product Image |  | |||
within mammalian cells that display an immune response. Their versatility extends to serving as a suitable host for transfection experiments, making PC-3 cells a versatile tool for researchers across diverse fields. They are particularly valuable for investigating the intricacies of the tumor environment and evaluating the efficacy of therapeutic drugs.- ONLINE INQUIRY
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