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Transfected Stable Cell Lines

LS-174T (NFkB) Luciferase Reporter Cell Line

  • For research use only

Cat No.

ABC-RC472H
Product Type

Reporter Stable Cell Line
Cell Type

Epithelial

Host Cell

LS-174T Cell Line
Source Organ

Large Intestine; Colon
Disease

Adenocarcinoma
Storage

Liquid Nitrogen

LS-174T (NFkB) Luciferase Reporter Cell Line ,LS-174T cells stably expressing luciferase; model for NF-κB signaling, cancer biology and drug screening.

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  • LS-174T (NFkB) Luciferase Reporter Cell Line
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Home | Transfected Stable Cell Lines | Reporter Stable Cell Lines | LS-174T (NFkB) Luciferase Reporter Cell Line

Description

The LS-174T (NFkB) Luciferase cell line is transformed from LS-174T cell, expressing the firefly luciferase gene. The cell constitutively express Luciferase.

Product Code

LS-174T (NFkB) Luciferase Cell Line
Cat.No

ABC-RC472H
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial

Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Large Intestine; Colon
Disease

Adenocarcinoma
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Reporter Stable Cell Line
Host Cell

LS-174T Cell Line
Stock

In Stock
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Frequently Asked Questions

  • Can this cell line be used for in vivo tumor growth tracking by bioluminescence imaging?

    This cell line is a pathway-specific luciferase reporter model designed to monitor activation of the NF-κB signaling pathway. The luminescence signal reflects NF-κB pathway activity rather than constitutive luciferase expression or stable cell number.

    As a result, the bioluminescent signal is not directly correlated with tumor burden and may fluctuate depending on pathway activation status. Therefore, this cell line is not recommended for in vivo tumor growth tracking applications where luciferase signal intensity is expected to correlate quantitatively with cell number.

    For in vivo bioluminescence imaging of tumor growth, a constitutively luciferase-expressing stable cell line is recommended. Such models provide stable, high-level luciferase expression, allowing reliable detection of luciferin-dependent signals that correlate with tumor cell proliferation and burden.

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