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MCF-12A

Product Name

MCF-12A

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Product Code

MCF12A

Cat.No

ABC-TC0639

Species

Human

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

MCF-12A, a non-malignant breast cancer cell line, was extracted from the mammary gland of a 60-year-old White female patient who had fibrocystic breast disease with intraductal hyperplasia. Derived through a reduction mammoplasty procedure from a nulliparous individual, these cells predominantly exhibit an epithelial morphology. In culture, they adhere in small patches, gradually forming domes as they reach confluence. These patches, varying in size, cluster more tightly with higher cell density. Notably, the MCF-12A cell line often shows the presence of floaters and debris. This cell line is a valuable resource for research related to non-malignant breast cancer.

 

Why choose MCF-12A from AcceGen?

MCF-12A cell line boasts high quality and viability, ensuring reliable research outcomes. It is maintained in sterile conditions, rigorously tested for mycoplasma contamination, and its identity is verified through STR analysis. The cells are carefully cryopreserved by experienced operators, and stringent quality control measures are consistently applied to maintain their integrity and reliability in experimental settings.

Source Organ

Breast

Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

FOR RESEARCH USE ONLY

MCF-12A cell line finds versatile applications in breast cancer research, enabling the exploration of genes’ roles in breast cancer pathophysiology and the identification of genomic and transcriptional features in breast cancer cells. These insights aid in predicting responses to targeted therapies and other physiological changes. Moreover, MCF-12A is valuable for 3D culture studies, facilitating investigations into proliferation, signaling protein expression, and gene expression. It also highlights consistent differences in genes encoding signal transduction proteins when studying tumor cells within 3D microenvironments, offering critical insights into breast cancer biology.

Growth Conditions

37 ℃, 5% CO2

Cell Type

Epithelial

Growth Mode

Adherent

Product Type

Human Skin Cell Lines

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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