Monkey Aortic Endothelial Cells

Description

Monkey Aortic Endothelial Cells are primary endothelial cells isolated from monkey aorta and cryopreserved after initial culture, and are occasionally used alongside transcriptomic datasets such as cynomolgus monkey aorta RNA to contextualize endothelial gene expression and vascular functional profiles. They display typical cobblestone morphology and express endothelial markers including CD31, VE-Cadherin, and von Willebrand factor (vWF), alongside functional uptake of acetylated LDL. These cells contribute to vascular homeostasis, angiogenesis, and blood vessel tone regulation. They have been implicated in pancreatic bud induction and insulin-producing cell differentiation, as well as arterial wall inflammation. Due to their physiological similarity to human endothelial cells, they are valuable for cardiovascular disease, vascular inflammation, and atherosclerosis research. Their gene expression reflects endothelial function and shear stress response. These cells are non-proliferative in vitro, cannot be passaged, and repeated freeze-thaw cycles should be avoided to maintain viability.