Monkey Cardiac Fibroblasts

Description

Monkey Cardiac Fibroblasts (MCFs) are primary fibroblasts isolated from cardiac tissue of the Cynomolgus Monkey. These cells represent heart-derived mesenchymal fibroblasts and typically exhibit spindle-shaped or stellate morphology with adherent growth characteristics under standard in vitro culture conditions. Cardiac fibroblasts are essential stromal cells within the heart and play a critical role in maintaining myocardial structural integrity. They contribute to the synthesis, deposition, and remodeling of extracellular matrix (ECM) components and participate in tissue repair and cardiac remodeling processes. MCFs typically express the fibroblast-associated marker Vimentin. To ensure the quality of these primary cells, repeated freeze-thaw cycles are not recommended due to the fragile nature of these cells. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.