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Primary Cells

Mouse Podocytes

  • For research use only

Cat No.

ABC-TC3933

Product Type

Mouse Primary Cells

Cell Type

Podocyte

Species

Mouse

Growth Conditions

37 ℃, 5% CO2

Disease

Normal

Storage

Liquid Nitrogen

Mouse podocytes, 2-week ICR mouse.

Product Image

Description

Mouse Podocytes are primary cells isolated from the renal glomerular tissue of healthy mice. As specialized epithelial cells, they form the filtration barrier in the glomerulus, exhibiting a characteristic arborized or cobblestone-like morphology essential for maintaining the kidney filtration barrier. Functionally, podocytes maintain glomerular filtration integrity by regulating macromolecular permeability. Their dysfunction is central to glomerular diseases such as nephrotic syndrome and diabetic kidney disease. These mouse podocytes express podocyte-specific marker nephrin. These post-mitotic cells have limited proliferative capacity in vitro. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.

Product Code

Mouse Podocytes, Murine Podocytes, Glomerular Podocytes (Mouse), Kidney Filtration Cells

Species

Mouse

Cat.No

ABC-TC3933

Product Category

Primary Cells

Size/Quantity

1 vial

Cell Type

Podocyte

Growth Mode

Adherent

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Mouse Primary Cells

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Mouse Podocytes serve as an in vitro cell model to study the pathogenesis of glomerular diseases, such as focal segmental glomerulosclerosis (FSGS), diabetic nephropathy, and lupus nephritis. They enable researchers to investigate foot process effacement, slit diaphragm protein expression, and response to inflammatory cytokines or metabolic stress, thereby gaining insights into molecular pathways underlying podocyte dysfunction. This supports discovery research and molecular target identification related to proteinuric kidney diseases and renal fibrosis associated with aberrant podocyte physiology in maintaining glomerular filtration barrier integrity and pathological dysregulation in disease.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Frequently Asked Questions

  • How are Mouse Podocytes isolated and what quality control measures are used to ensure they are podocytes?

    1. The primary mouse podocytes are isolated through glomerular screening combined with differential adhesion techniques.
    2.The cells are confirmed positive for PCK or WT-1 (Wilm’s Tumor Protein) via immunofluorescence staining, with a purity of over 90%.

Inquiring Mouse Podocytes

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