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| Species | Mouse |
| Cat.No | ABC-TC3937 |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
| Product Category | Primary Cells |
| Size/Quantity | 1 vial |
| Cell Type | Splenocyte |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Spleen |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Mouse Primary Cells |
Mouse Splenocytes are primary immune cells isolated from the spleen tissue of mice (Mus musculus), They constitute a heterogeneous population of lymphocytes, including T-cells, B-cells, Natural Killer (NK) cells, and NKT-cell. These cells are derived from normal, disease-free donors and are cryopreserved after isolation to maintain high viability and functionality. Morphologically, splenocytes are mononuclear and maintained in suspension culture. They play an important role in adaptive immunity, including antigen presentation, antibody production, and cytokine secretion. They are widely utilized in research on autoimmune diseases, such as type 1 diabetes and multiple sclerosis. These cells express characteristic surface markers like CD3 (T-cells), CD19/CD45R (B-cells), CD4 (helper T-cells), and CD8 (cytotoxic T-cells). Due to their sensitivity to freeze-thaw cycles, repeated cryopreservation should be avoided to preserve cell integrity.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
Mouse splenocytes play a pivotal role in a wide array of immunological research applications. They are commonly employed in various in-vitro immunoassays, including but not limited to ELISPOT, mixed lymphocyte reactions, and cytotoxicity assays measuring antibody-dependent cellular cytotoxicity (ADCC) or complement-dependent cytotoxicity (CDC). Moreover, their significance extends to ex-vivo applications for comprehensive immune cell population profiling and genetic modification via retroviral transduction. These capabilities highlight their indispensable role in advancing immunological research and therapeutic discovery.
