Primary Cells

Mouse Splenocytes

  • For research use only

Cat No.

ABC-TC3937

Product Type

Mouse Primary Cells

Cell Type

Splenocyte

Species

Mouse

Growth Conditions

37 ℃, 5% CO2

Source Organ

Spleen

Disease

Normal

Storage

Liquid Nitrogen

Mouse Splenocytes include T/B/NK/NKT cells, support immune response modeling, and are useful in autoimmune disease and lymphocyte function studies.

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Description

Mouse Splenocytes are primary immune cells isolated from the spleen tissue of mice (Mus musculus), they constitute a heterogeneous population of lymphocytes, including T-cells, B-cells, Natural Killer (NK) cells, and NKT-cell. These cells are derived from normal donors and are cryopreserved after isolation to maintain high viability and functionality. Morphologically, splenocytes are mononuclear and maintained in suspension culture. They play an important role in adaptive immunity, including antigen presentation, antibody production, and cytokine secretion. They are widely utilized in research on autoimmune diseases, such as type 1 diabetes and multiple sclerosis. These cells express characteristic surface markers like CD3 (T-cells), CD19/CD45R (B-cells), CD4 (helper T-cells), and CD8 (cytotoxic T-cells). Due to their sensitivity to freeze-thaw cycles, repeated cryopreservation should be avoided to preserve cell integrity.

Species

Mouse

Cat.No

ABC-TC3937

Product Category

Primary Cells

Size/Quantity

1 vial

Cell Type

Splenocyte

Growth Mode

Adherent

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Spleen

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Mouse Primary Cells

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Mouse splenocytes play a pivotal role in a wide array of immunological research applications. They are commonly employed in various in-vitro immunoassays, including but not limited to ELISPOT, mixed lymphocyte reactions, and cytotoxicity assays measuring antibody-dependent cellular cytotoxicity (ADCC) or complement-dependent cytotoxicity (CDC). Moreover, their significance extends to ex-vivo applications for comprehensive immune cell population profiling and genetic modification via retroviral transduction. These capabilities highlight their indispensable role in advancing immunological research and therapeutic discovery.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Inquiring Mouse Splenocytes

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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