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Primary Cells

Mouse Splenocytes CD19+ B Cells

  • For research use only

Cat No.

ABC-TC3938
Product Type

Mouse Primary Cells
Cell Type

B Cell
Species

Mouse
Growth Conditions

37 ℃, 5% CO2
Source Organ

Spleen
Disease

Normal
Storage

Liquid Nitrogen

Mouse spleen is dissociated into a single cell suspension.

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  • Mouse Splenocytes CD19+ B Cells
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Home | Primary Cells | Animal Primary Cells | Mouse Primary cells | Mouse Splenocytes CD19+ B Cells

Description

Mouse Splenocytes CD19+ B Cells are isolated from the spleen tissue of healthy mice and positively selected for CD19 expression. These cells exhibit a characteristic round morphology in suspension culture. Functionally, CD19+ B cells play a central role in humoral immunity by producing antibodies, presenting antigens, and regulating immune responses, with dysregulation associated with autoimmune diseases like lupus and B-cell lymphomas. The cells express CD19. These primary B cells have limited proliferative capacity in vitro. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.​

Product Code

Mouse Splenocytes CD19+ B Cells, Mouse CD19+ B Cells, Murine Splenic B Lymphocytes, CD19 Positive B Cells (Mouse)
Species

Mouse
Cat.No

ABC-TC3938
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

B Cell
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Spleen
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Mouse Primary Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Mouse Splenocytes CD19+ B Cells can be used as an in vitro cell model to study the pathogenesis of autoimmune diseases, humoral immune disorders, and lymphoproliferative diseases, such as systemic lupus erythematosus (SLE), rheumatoid arthritis, and B-cell lymphoma, which enables researchers to investigate antibody secretion profiles, plasma cell differentiation kinetics, and responses to T-cell-derived signals and autoantigens. These studies yield valuable insights into the molecular pathways underlying B-cell dysfunction, and provide a better understanding of CD19+ B cells’ physiological roles in adaptive immunity and their pathological alterations in disease, supporting discovery research and molecular target identification for immune-mediated disorders and B-cell-related malignancies.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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