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Tumor Cell Lines

MPP 89

  • BSL

    2

  • 266
Species: human male 67 years old; Tissue: pleural effusion; Tumor: mesothelioma.
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Product Code

MPP-89; MPP89

Species

Human

Cat.No

ABC-TC0701

Product Category Tumor Cell Lines
Size/Quantity

1 vial

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Biosafety Level

2

Storage

Liquid Nitrogen

Product Type

Human Mesothelioma Cell Lines

Description

MPP 89
MPP 89 is a human mesothelioma cell line that was originally isolated from the pleural effusion of a 67-year-old patient with malignant mesothelioma. MPP 89 exhibits epithelial-like morphology and adherent culture properties.MPP-89 cells were characterized as hyperdiploid, bearing deletions/translocations of chromosome 6, chromosome 13 monosomy, and lacking both chromosomes 17. Immunohistochemical analysis shows positivity for CAM 5.2, HBME-1, and Calretinin, while it is negative for Z-CEA, LeuM1, LeuM6, and LeuM3. MPP 89 is non-tumorigenic.
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Citation

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Application

  • The MPP 89 cell line is a vital resource in malignant mesothelioma research. It serves as a platform for the development of therapeutic immunotherapies and for the evaluation of microRNA (miRNA) expression profiles. These studies aid in identifying diagnostic and prognostic markers and contribute to improved disease classification and the advancement of personalized treatment strategies for mesothelioma.

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High Viability
To succeed in cell culture
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To support a consistent result
Customization Options
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