For research use only
| Cat No. | ABC-TC0701 |
| Product Type | Human Mesothelioma Cell Lines |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Product Code | MPP-89; MPP89 |
MPP 89, a hyperdiploid mesothelioma cell line from pleural effusion. Delve into its morphology and key immunohistochemical markers.
MPP 89 is a human malignant pleural mesothelioma cell line derived from the pleural effusion of a 67-year-old male patient diagnosed with malignant mesothelioma. The cells exhibit spindle-shaped, epithelial-like morphology and grow adherently in culture. Cytogenetic analysis reveals an abnormal hyperdiploid karyotype, notably characterized by the loss of both copies of chromosome 17. Gene expression profiling indicates alterations in pathways related to cell proliferation, apoptosis, and DNA repair, reflecting the malignant phenotype. MPP 89 displays a transcriptional signature typical of epithelioid mesothelioma, with upregulation of mesothelioma-specific markers. Although exhibiting some tumorigenic properties in vitro, MPP 89 cells do not readily form tumors in immunodeficient mice, making them a valuable in vitro model for studying mesothelioma biology and marker expression.
| Product Code | MPP-89; MPP89 |
| Species | Human |
| Cat.No | ABC-TC0701 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Biosafety Level | 2 |
| Storage | Liquid Nitrogen |
| Product Type | Human Mesothelioma Cell Lines |
The MPP 89 cell line is a vital resource in malignant mesothelioma research. It serves as a platform for the development of therapeutic immunotherapies and for the evaluation of microRNA (miRNA) expression profiles. These studies aid in identifying diagnostic and prognostic markers and contribute to improved disease classification and the advancement of personalized treatment strategies for mesothelioma.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
