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Home > Products > Animal Tumor Cell Lines >

Nb2-11

Product Name

Nb2-11

Cat.No

ABC-TC5569

Product Type

Rat Lymphoma Cell Lines

Species

Rat

Size/Quantity

1 vial

Shipping Info

Dry ice

Storage

Liquid Nitrogen

Description

Nb2-11 is a clone of the Nb-2 rat lymphoma line which was derived from a transplant of a lymphoma that developed in the thymus/lymph node of a male noble (Nb) strain rat following prolonged oestrogen treatment. The cells are of the pre-T cell origin and their proliferation is dependent on mammalian lactogens, such as prolactin. Nb2-11 can also be mitogenically stimulated by IL-2. Injection of Nb2 cells into Nb rats gives rise to malignant tumours that are highly sensitive to treatment with vinca alkaloids. Karyotypic analysis has shown that the cell line has only five well developed chromosome abnormalities.

Citation Guide

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Application

For research use only

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