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| Product Code | NFS-70 C-10; NFS70 |
| Species | Mouse |
| Cat.No | ABC-TC0822 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Lymphoblast |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Blood |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Mouse Lymphocytes Cell Lines |
NFS-70 C10 is a murine pro-B lymphoblast cell line derived from a lymphoma induced by murine leukemia virus (MuLV) in an NFS/N strain mouse. The cell exhibit typical lymphoblast morphology and grow in suspension culture. This model retains key markers of early B-cell differentiation, including CD5, CD32 (FcγRII), and CD45R (B220), alongside Mac-1 (CD11b), while lacking surface immunoglobulin and Ia antigens. Its immunophenotype (CD5+/CD32+/CD45R+) aligns with pro-B lineage commitment, making it a valuable resource for studying early lymphoid development and hematologic malignancies.
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The NFS-70 C10 cell line holds plays a significant role in immunology and retrovirology research, particularly in (murine leukemia virus) MuLV research. It is widely used to investigate B lymphopoiesis and the regulation of lymphoid developement by cytokines. NFS-70 C10 cells enables researchers to explore how specific cytokines influence the B lineage cells differentiation and proliferation, providing insights into immune system development and the mechanisms underlying lymphoid malignancies.
