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| Product Code | OSCA-8; OSCA8; OSA8 |
| Species | Canine |
| Cat.No | ABC-TC5571 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Shipping Info | Dry ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Storage | Liquid Nitrogen |
| Product Type | Canine Sarcoma Cell Lines |
OSCA-8, an osteosarcoma cell line, originates from a left-shoulder tumor in a 1-year-old male Rottweiler. It thrives in vitro and gives rise to both orthotopic and heterotopic tumor xenografts in immunodeficient mice. Its gene expression profile aligns with the most aggressive molecular phenotype of osteosarcoma.
This type of cancer emerges from primitive transformed cells of mesenchymal origin, demonstrating osteoblastic differentiation and generating malignant osteoid.
Why choose OSCA-8 from AcceGen?
OSCA-8 from AcceGen is preferred as a high-quality and highly viable cell product. AcceGen ensures professional handling with optimal incubation conditions. The cells are rigorously tested through STR profiling to eliminate mycoplasma contamination and any presence of mouse, rat, Chinese hamster, or African green monkey contaminants. Additionally, OSCA-8 is authenticated using a canine STR marker, enhancing its credibility and practicality.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
FOR RESEARCH USE ONLY
The OSCA-8 cell line’s relevance lies in its application to address the challenges of canine osteosarcoma, characterized by high metastasis rates and a grim prognosis. It serves as a valuable tool to examine inhibitor cytotoxicity, elucidate resistance mechanisms against established drugs, and innovate novel therapeutic approaches to induce apoptosis. OSCA-8 contributes significantly to advancing the understanding and management of this aggressive disease in canines.
