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Tumor Cell Lines

OVKATE

  • BSL

    1

  • 487
Ovarian adenocarcinoma. Cells are transplantable to both mouse hypodermis and abdominal.
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Home | Tumor Cell Lines | Human Tumor Cell Lines | OVKATE
Species

Human
Cat.No

ABC-TC0882
Product Category Tumor Cell Lines
Size/Quantity

1 vial
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Ovary
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Human Ovarian Cancer Cell Lines

Description

OVKATE human ovarian serous adenocarcinoma cells exhibit polygonal, epithelial morphology; scale bar at bottom right.
OVKATE is a human ovarian cancer cell line that was originally isolated from the solid tumor of a patient with serous papillary adenocarcinoma. OVKATE exhibits epithelial-like morphology and adherent culture properties. This cell line expresses a variety of cytokeratins (CK6, 7, 8, 13, 17, 18, 19, 20, 15 ,and/or 16), and is positive for vimentin, epithelial membrane antigen (EMA), and epidermal growth factor receptor (EGFR). It is negative for desmin, S-100, myoglobin, type II collagen, α-smooth muscle actin, and glial fibrillary acidic protein (GFAP). OVKATE is tumorigenic.
AcceGen Frozen Cells & Cell Lines 1 vial
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Citation

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Application

  • The OVKATE cell line is a key model for human ovarian carcinoma research. It is used in genomics studies and for establishing xenograft models, allowing in-depth exploration of the molecular mechanisms underlying ovarian cancer. In addition, OVKATE cells support investigations into the regulation of intermediate filament expression and are employed in testing the anti-proliferative effects of candidate drugs, facilitating the development of innovative therapies for ovarian cancer.

Frequently Asked Questions

  • What are OVKATE cells?

    OVKATE cells were originally isolated from ovary of a stage IIIc ovarian tumor patient.

  • What is the doubling time of OVKATE cell line?

    The OVKATE cell line grow slowly. The doubling time would be over 1 week.

  • Is OVKATE cell line tumorgenic?

    Yes. Cells are form tumors by SC injection.

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