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OVKATE

  • BSL

    1

  • 340
Ovarian adenocarcinoma. Cells are transplantable to both mouse hypodermis and abdominal.
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Home | Tumor Cell Lines | Human Tumor Cell Lines | OVKATE
Species

Human
Cat.No

ABC-TC0882
Product Category Tumor Cell Lines
Size/Quantity

1 vial
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Ovary
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Human Ovarian Cancer Cell Lines

Description

OVKATE
OVKATE is a human ovarian carcinoma cell line derived from a serous papillary adenocarcinoma solid tumor. These cells express various cytokeratins (CKs 6, 7, 8, 13, 17, 18, 19, 20, 15, and/or 16) and are negative for CKs 10 and 14. Additionally, OVKATE cells are positive for vimentin, EMA, and EGF receptors, while negative for desmin, S-100, myoglobin, type II collagen, α-smooth muscle actin, and glial fibrillary acidic protein. They exhibit transplantability to both mouse hypodermis and abdominal regions, forming tumors with sheet-like structures, solid nests, or papillary structures composed of oval- to spindle-shaped cells.

 

Why choose OVKATE from AcceGen?

The OVKATE cell line from AcceGen is characterized by high viability and exceptional quality. It is provided in a sterile condition, ensuring it is free from contaminants such as bacteria, fungi, and mycoplasma. Furthermore, real-time PCR has confirmed its negative status for human pathogens, making it a reliable and safe resource for research applications.

AcceGen Frozen Cells & Cell Lines 1 vial
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Citation

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Application

  • FOR RESEARCH USE ONLY

  • The OVKATE cell line serves as a vital resource in the field of human ovarian carcinoma research. It is employed for genomics studies and the creation of xenograft models, enabling in-depth investigations into the molecular mechanisms underlying this cancer type. Furthermore, OVKATE cells offer a valuable experimental system for the study of regulatory control mechanisms related to intermediate filament expression. Additionally, they are instrumental in testing the anti-proliferative effects of potential drugs, facilitating the evaluation of novel therapeutic approaches in the context of ovarian carcinoma.

Frequently Asked Questions

  • What are OVKATE cells?

    OVKATE cells were originally isolated from ovary of a stage IIIc ovarian tumor patient.

  • What is the doubling time of OVKATE cell line?

    The OVKATE cell line grow slowly. The doubling time would be over 1 week.

  • Is OVKATE cell line tumorgenic?

    Yes. Cells are form tumors by SC injection.

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