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OVMANA | ||||
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Product Name | OVMANA | |||
Price | Get Quote | |||
Cat.No | ABC-TC0883 | Species | Human | |
Size/Quantity | 1 vial | Biosafety Level | 1 | |
Shipping Info | Dry Ice | Storage | Liquid Nitrogen | |
Description | OVMANA cells are derived from a stage IV ovarian clear cell carcinoma (OCCC) patient who received prior cisplatin treatment. These Japanese-origin cells display copy number aberrations throughout the genome and mutations in OCCC-related genes (ARID1A, PIK3CA, KRAS, PTEN). They express HNF1-β, Napsin A, and cytokeratin polypeptides (CKs 6, 7, 8, 18, 19, 20, 15, and/or 16), as well as wild-type p53. OVMANA cells can be cultured at 37 °C using RPMI-1640 medium supplemented with 10% fetal bovine serum (FBS).
Why choose OVMANA from AcceGen? The OVMANA cell product from AcceGen is prepared under sterile conditions to ensure its safety and purity. It exhibits high viability and quality; a significant proportion of the cells remain alive and functional after thawing. The cells can maintain a good cell state with intact morphology, physiological characteristics, and functionality. Rigorous quality control measures are implemented throughout the production process to meet defined specifications and maintain consistency. The entire operation is conducted by skilled professionals who possess expertise in cell culture techniques, ensuring the utmost care and precision. These features collectively contribute to a reliable, high-quality OVMANA cell product that meets the stringent standards of quality control and professional operation. | |||
Source Organ | Ovary | |||
Recommended Medium And Supplement | RPMI 1640 + 10% FBS | |||
Citation Guide | When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID). | |||
Application | FOR RESEARCH USE ONLY OVMANA cells, derived from ovarian clear cell carcinoma (OCCC), have significant applications in the scientific field. They promote understanding of this rare subtype of ovarian cancer, which lacks efficient treatment options, by unraveling its molecular mechanisms and genetic abnormalities. OVMANA cells serve as a model for testing chemicals and potential drugs, evaluating their ability to induce cell death or autophagy in OCCC. This enables the identification of promising candidates for OCCC treatment. Additionally, these cells aid in investigating the high resistance of OCCC to standard chemotherapy, facilitating the development of novel therapeutics to overcome this resistance and improve patient outcomes. In summary, OVMANA cells contribute to understanding OCCC, facilitate drug testing, and advance research on overcoming chemotherapy resistance in OCCC. | |||
Growth Conditions | 37 ℃, 5% CO2 | |||
Product Type | Human Ovarian Cancer Cell Lines | |||
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