Porcine Lens Epithelial Cells

Description

Porcine Lens Epithelial Cells (PLEC) are primary epithelial cells isolated from the anterior surface of the lens in healthy swine. The cells originate from normal ocular tissue and are harvested under sterile conditions. They form a monolayer of cuboidal cells tightly attached to the lens capsule and exhibit adherent growth in vitro. These cells are cryopreserved at early passage to preserve viability and phenotype. Functionally, they regulate lens homeostasis, electrolyte balance, and fiber cell differentiation. PLEC express lens-specific markers such as αA-crystallin, connexin-43, and N-cadherin, which indicate epithelial identity and lens-specific function. Each lot undergoes rigorous screening and isolation procedures and is tested to ensure it is free from contamination by Mycoplasma, Fungi, Yeast, and Bacteria.