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Tumor Cell Lines

QGP-1

  • For research use only

Cat No.

ABC-TC0918

Product Type

Human Pancreas Cancer Cell Lines

Cell Type

Epithelial-like

Species

Human

Growth Conditions

37 ℃, 5% CO2

Source Organ

Pancreas

Product Code

QGP 1; QGP1

QGP-1 is a pancreatic neuroendocrine tumor cell line expressing CEA, SSTR2/5, used in pNET studies and neuroendocrine drug screening models.

Product Image

Description

Brightfield micrograph of QGP-1, showing adherent growth, 4X magnification.
QGP-1 is a human pancreatic neuroendocrine tumor cell line derived from the pancreas of a male patient with a carcinoid tumor. These epithelial-like cells are polygonal or rounded and grow adherently in standard culture conditions (37°C, 5% CO₂). The cell line expresses neuroendocrine markers such as carcinoembryonic antigen (CEA) and synaptophysin, and shows elevated expression of transcription factors related to neuroendocrine differentiation, immature pancreatic β/δ-cell genes. The cell line exhibits genomic instability, with a portion of the cells showing a tetraploid karyotype. This cell line also exhibits the expression of somatostatin receptors (SSTR2 and SSTR5), making it an important in vitro model for studying pancreatic neuroendocrine tumors (pNETs).
Product Code

QGP 1; QGP1

Species

Human

Cat.No

ABC-TC0918

Product Category Tumor Cell Lines
Size/Quantity

1 vial

Cell Type

Epithelial-like

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Pancreas

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Human Pancreas Cancer Cell Lines

Application

  • QGP-1 cell line can serve as an in vitro cell model for neuroendocrine tumor (NET) drug development. In addition, the QGP-1 cell line is also an excellent model for studying human enterochromaffin (EC) cells. Because it highly expresses EC cell marker genes and transient receptor potential ankyrin 1 (TRPA1), it can be used to further explore the function and regulatory mechanism of TRPA1 in EC cells.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
Si, Y., Kim, S., Guenter, R., Ou, J., Lu, Y., Chen, K., Zhang, J., Whitt, J., Carter, A.M., Bibb, J.A. and Jaskula-Sztul, R., 2019. Anti-SSTR2 Antibody-Drug Conjugate for Neuroendocrine Cancer Therapy. bioRxiv, p.688184.
Si Y, Guan J, Xu Y, et al. Dual-Targeted Extracellular Vesicles to Facilitate Combined Therapies for Neuroendocrine Cancer Treatment. Pharmaceutics. 2020;12(11):1079. Published 2020 Nov 11. doi:10.3390/pharmaceutics12111079
Herring, B., Jang, S., Whitt, J., Goliwas, K., Aburjania, Z., Dudeja, V., Ren, B., Berry, J., Bibb, J., Frost, A. and Chen, H., 2021. Ex Vivo Modeling of Human Neuroendocrine Tumors in Tissue Surrogates. Frontiers in endocrinology, 12.

Inquiring QGP-1

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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