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T3M-4

Product Name

T3M-4

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Product Code

T3M4; Panc89; Panc-89; PANC-89; Panc 89

Cat.No

ABC-TC1324

Species

Human

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

T3M-4 cells are a human carcinoembryonic antigen (CEA)-producing cell line derived from a primary human pancreatic exocrine adenocarcinoma transplanted into nude mice. These cells exhibit epithelial features similar to the original tumor and grow as a monolayered sheet with a population doubling time of about 31 hours. They demonstrate tumorigenicity in athymic nude mice and maintain their original histology through serial transplantation. The cell line is a human aneuploid one with a hyperdiploid mode, as confirmed by chromosomal analysis. T3M-4 cells secrete CEA both in vitro and in vivo when used to generate tumors in nude mice.

 

Why choose T3M-4 from AcceGen?

T3M-4 cells from AcceGen are an excellent choice due to their high viability, sterile nature, and optimal incubation and cryopreservation conditions using advanced techniques. These cells undergo rigorous quality control measures and are safely transported, ensuring reliable and consistent performance for research and experimentation purposes.

Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

FOR RESEARCH USE ONLY

The T3M-4 cell line has several valuable applications in the field of human pancreatic cancer research. Firstly, it can be used to identify the gene profile of human pancreas carcinoma, enabling the analysis of oncogene activation as well as aberrant expression and epigenetic changes of genes specific to pancreatic cancer. This aids in understanding the molecular mechanisms underlying the disease. Additionally, T3M-4 cells serve as a useful tool for evaluating the anti-tumor potential of antibodies or drugs, facilitating the development of novel therapeutic strategies for treating human pancreatic cancer. By assessing the efficacy of different treatments, researchers can advance the search for effective therapies targeting this challenging malignancy.

Growth Conditions

37 ℃, 5% CO2

Product Type

Human Pancreas Cancer Cell Lines

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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