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Transfected Stable Cell Lines

Raw264.7/STAT5 Reporter (GFP) Stable Cell Line

  • For research use only

Cat No.

ABC-RC012Y
Product Type

Reporter Stable Cell Lines
Cell Type

Monocyte
Species

Mouse
Host Cell

Raw264.7
Source Organ

Blood / Macrophage
Disease

Leukemia
Storage

Liquid Nitrogen

Raw264.7/STAT5 Reporter (GFP) Stable Cell Line visualizes STAT5 signaling via GFP in real-time for immunology and inflammatory response research.

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  • Raw264.7/STAT5 Reporter (GFP) Stable Cell Line
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Home | Transfected Stable Cell Lines | Raw264.7/STAT5 Reporter (GFP) Stable Cell Line

Description

Raw264.7/STAT5 Reporter (GFP) stable Cell Line is a genetically engineered macrophage model derived from the murine Raw264.7 cell line, designed for monitoring STAT5 (Signal Transducer and Activator of Transcription 5) signaling activity through green fluorescent protein (GFP) expression. This cell line retains its monocyte/macrophage origin and adherent morphology while exhibiting key macrophage functions such as cytokine secretion and phagocytosis. The integrated STAT5-responsive GFP reporter allows real-time tracking of STAT5 pathway activation, making it ideal for immunology and inflammation research. Key markers include CD14 and F4/80, with GFP fluorescence serving as a direct readout of STAT5 transcriptional activity. The cells are maintained at low passage numbers (<P20) to ensure genetic stability. The cells have undergone rigorous quality control testing and are confirmed free of contamination from mycoplasma, fungi, yeast, and bacteria.

Species

Mouse
Cat.No

ABC-RC012Y
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Monocyte
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Blood / Macrophage
Disease

Leukemia
Biosafety Level

2
Storage

Liquid Nitrogen
Product Type

Reporter Stable Cell Lines
Host Cell

Raw264.7
Gene Info

GFP (STAT5-responsive reporter)
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • The Raw264.7/STAT5 Reporter (GFP) Stable Cell Line monitors STAT5 signaling via GFP expression, enabling real-time detection and direct visualization of JAK-STAT pathway activation in macrophages. This system allows quantitative assessment of STAT5-mediated responses to cytokines and drugs at single-cell resolution. Ideal for studying macrophage polarization and tumor microenvironment interactions, it facilitates high-content screening of STAT5 inhibitors. The GFP readout provides insights into STAT5 activation during immune cell-tumor crosstalk, supporting research on macrophage functions in cancer and inflammation.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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