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Recombinant Human IL-4 Protein

  • For research use only

Cat No.

ABC-GF0012
Product Type

Others

IL-4 (interleukin 4) is a cytokine that regulates B and T cell activation, IgE production, Th2 differentiation, and immune responses in allergy research.

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  • Recombinant Human IL-4 Protein
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Home | Cell Culture Media, Kits & Reagents | Growth Factors & Cytokines | Recombinant Human IL-4 Protein

Description

IL-4 (interleukin 4), also known as IL4, is a secreted protein that belongs to the IL-4 / IL-13 family. IL-4 has many biological roles, including the stimulation of activated B-cell and T-cells. It enhances both secretion and cell surface expression of IgE and IgG1. IL-4 also regulates the expression of the low-affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. IL-4 is essential for the switching of B cells to IgE antibody production and the maturation of T helper (Th) cells toward the Th2 phenotype. It participates in at least several B-cell activation processes as well as other cell types. IL-4 plays a crucial role in modulating immune responses and is widely used in studies of allergy, asthma, and T helper cell differentiation.

Species

Human
Cat.No

ABC-GF0012
Product Category

Cell Culture Media, Kits & Reagents
Size/Quantity

20 µg/100 µg/1 mg
Shipping Info

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage

-20°C
Product Type

Others
Concentration

≥ 95 % as determined by SDS-PAGE and SEC-HPLC.
Buffer Mix

Lyophilized from sterile PBS, pH 7.4.
Please contact us for any concerns or special requirements.
Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Key Features

< 5 EU per mg of the protein

Quality Control

HPLC-verified. GMP grade is also available

Application

  • IL-4 can be developed for use in cell culture, functional assays, and differentiation studies. IL-4 supplement at a high concentration can protect responder T cells (Tresps) from Treg-mediated immune suppression.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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