For research use only
| Cat No. | ABC-GF0036 |
| Product Type | Others |
Activin protein is composed of two β subunits, βA βA (activin A), βB βB (activin B), or βA βB (activin AB), produced in many cell types and organs.
Activins are growth factors with multiple roles in the development and homeostasis. Activins are disulfide-linked homo- and heterodimers of four inhibin β chains, Activins A are homodimers formed from inhibin βA. Activin A is a member of the transforming growth factor beta (TGF-β) family of proteins produced by many cell types throughout development. Activin-A initiates signaling by binding to a heteromeric complex of two type I and two type II serine/threonine kinase receptors. This binding activates the receptor kinases, leading to the phosphorylation of intracellular mediators SMAD2 and 3. These phosphorylated SMADs complex with SMAD4, translocate to the nucleus, and regulate gene expression.
| Species | Human, Mouse, Rat, Cynomolgus, Rhesus, Rabbit |
| Cat.No | ABC-GF0036 |
| Product Category | Cell Culture Media, kits & Reagents |
| Size/Quantity | 20 µg/100 µg/1 mg |
| Shipping Info | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. |
| Storage | -20°C |
| Product Type | Others |
| Concentration | ≥ 95 % as determined by SDS-PAGE and SEC-HPLC. |
| Key Features | < 10 EU per mg protein |
| Quality Control | HPLC-verified. GMP grade |
Activin A is a protein that regulates cell proliferation, differentiation, and maintains undifferentiated stem cells.