For research use only
| Cat No. | ABC-GF0034 |
| Product Type | Others |
Platelet-derived growth factor (PDGF) plays a crucial role in the connective tissue cell growth regulation, including fibroblasts and smooth muscle cells.
Platelet-derived growth factor (PDGF) was discovered as a major mitogenic factor present in serum but absent from plasma. In vitro, PDGF-BB stimulated MAP kinase activity and cell motility of isolated lymphatic endothelial cells. In vivo, PDGF-BB potently induced growth of lymphatic vessels. Expression of PDGF-BB in murine fibrosarcoma cells induced tumor lymphangiogenesis, leading to enhanced metastasis in lymph nodes. The PDGF signaling system contributes to vascular remodeling. Growth factors such as PDGF exert potent effects on wound healing including the regeneration of tooth-supporting structures.
| Species | Human |
| Cat.No | ABC-GF0034 |
| Product Category | Cell Culture Media, kits & Reagents |
| Size/Quantity | 20 µg/100 µg/1 mg |
| Shipping Info | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. |
| Storage | -20°C |
| Product Type | Others |
| Concentration | ≥ 95 % as determined by SDS-PAGE. ≥ 90% as determined by SEC-MALS. |
| Key Features | <50 EU per mg protein |
| Quality Control | MALS-verified |
PDGF-BB Protein is used for proliferation of hematopoietic stem and progenitor cell research. bFGF stimulated both capillary and arteriolar growth while PDGF-BB preferentially stimulated arterioles.