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Recombinant Mouse BMP4 Protein (rFc Tag)

  • For research use only

Cat No.

ABC-GF0029
Product Type

Others

BMP4 (bone morphogenetic protein-4) is a protein found in early embryonic development, directed differentiation of human embryonic stem cells (ESCd).

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  • Recombinant Mouse BMP4 Protein (rFc Tag)
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Home | Cell Culture Media, kits & Reagents | Growth Factors & Cytokines | Recombinant Mouse BMP4 Protein (rFc Tag)

Description

Bone morphogenetic protein 4 (BMP4) is a member of the transforming growth factor (TGF-β) family of regulatory proteins, plays a crucial role in human malignancies. BMP4 treatment can promote hepatocellular carcinoma cells (HCC) proliferation and induce autophagy. Mechanistic studies revealed that BMP4 induced autophagy is mediated through the activation of JNK1/Bcl2 pathway. JNK1 inhibition or knockdown attenuates BMP4 induced autophagy and abolishes BMP4 promoted HCC cell proliferation. BMP4 promoted HCC proliferation by autophagy activation through JNK1/Bcl-2 signaling.

Species

Mouse
Cat.No

ABC-GF0029
Product Category

Cell Culture Media, kits & Reagents
Size/Quantity

10 µg/100 µg
Shipping Info

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage

-20°C
Product Type

Others
Concentration

> 92 % as determined by SDS-PAGE.
Key Features

< 1.0 EU per μg protein as determined by the LAL method

Application

  • Mouse BMP-4 is used for stem cell differentiation, bone/cartilage formation, tissue repair, and early embryo differentiation.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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