Transfected Stable Cell Lines

RPMI-8226/Cre Stable Cell Line

  • For research use only

Cat No.

ABC-RC026Y

Product Type

Recombinase Stable Cell Line

Cell Type

B Lymphocyte

Species

Human

Host Cell

RPMI-8226

Source Organ

Peripheral Blood

Disease

Myeloma

Storage

Liquid Nitrogen

RPMI-8226/Cre Stable Cell Line by AcceGen enables efficient gene recombination and conditional knockout studies for advanced multiple myeloma research.

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Description

RPMI-8226/Cre Stable Cell Line is a genetically engineered human multiple myeloma model derived from RPMI-8226 cells, featuring stable expression of Cre recombinase. The cell line maintains characteristic plasma cell morphology and multiple myeloma surface markers (CD38, CD138) while providing efficient genome editing capability through Cre-mediated recombination of loxP-flanked genes. This makes it an essential tool for conditional knockout studies, functional genomics, and pathway analysis in hematological malignancies. Applications include investigating gene function, signaling pathways, tumor progression, and mechanisms of drug resistance. The cells are cryopreserved at low passage (<P20) to ensure stable Cre activity and consistent performance. All lots are rigorously tested to be free from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.

Species

Human

Cat.No

ABC-RC026Y

Product Category

Transfected Stable Cell Lines

Size/Quantity

1 vial

Cell Type

B Lymphocyte

Growth Mode

Suspension

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Peripheral Blood

Disease

Myeloma

Biosafety Level

2

Storage

Liquid Nitrogen

Product Type

Recombinase Stable Cell Line

Host Cell

RPMI-8226

Gene Info

Cre Recombinase

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • The RPMI-8226/Cre Stable Cell Line is engineered for conditional gene manipulation in multiple myeloma research. This model stably expresses Cre recombinase, enabling precise editing of loxP-flanked target genes in the RPMI-8226 background. The cell line is optimized for studying gene function in myeloma pathogenesis, validating therapeutic targets, and investigating drug resistance mechanisms. With consistent Cre activity and maintained myeloma characteristics, it provides a reliable platform for advanced genetic studies in hematological malignancy research.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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