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RT-112/84 | ||||
|---|---|---|---|---|
| Product Name | RT-112/84 | |||
| Price | Get Quote | |||
| Product Code | RT112-84; RT-112/84; RT11284 | |||
| Cat.No | ABC-TC0999 | Species | Human | |
| Size/Quantity | 1 vial | Biosafety Level | 1 | |
| Shipping Info | Dry Ice | Storage | Liquid Nitrogen | |
| Description |
Why choose RT-112/84 from AcceGen? The RT-112/84 cell line from AcceGen boasts high viability and quality, ensuring robust performance when incubated under optimal conditions. It is cryopreserved by experienced operators, undergoes rigorous quality control measures, and its identity is confirmed through STR analysis, ensuring its authenticity and reliability for research purposes. | |||
| Source Organ | Bladder | |||
| Recommended Medium And Supplement | EMEM + 10% FBS | |||
| Citation Guide | When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID). | |||
| Application | FOR RESEARCH USE ONLY The RT-112/84 cell line offers valuable applications in cancer research, serving as a critical tool for studying cancer cell invasion potential and the underlying mechanisms driving invasion induction. It is instrumental in tumorigenicity studies, aiding in the investigation of tumor formation and growth. Additionally, RT-112/84 cells have been utilized to assess the cytotoxic effects of compounds like lipoic acid and calcium hydroxycitrate, providing insights into potential therapeutic interventions for this cancer cell line. | |||
| Growth Conditions | 37 ℃, 5% CO2 | |||
| Cell Type | Epithelial | |||
| Growth Mode | Adherent | |||
| Product Type | Human Bladder Cancer Cell Lines | |||
| Product Image |  | |||
The RT-112/84 cell line is derived from human bladder carcinoma and exhibits an epithelial-like morphology. It is characterized by slow growth and an inability to form colonies in soft agar. When injected into nude mice, RT-112/84 cells display tumorigenic properties. Despite their tumorigenic properties, these cells display limited invasive behavior. These cells have a low plating efficiency, requiring 400 cells per dish to initiate colony formation. Additionally, RT-112/84 cells strongly express Claudin-11 and show high levels of E-cadherin, alpha-, beta-, and gamma-catenins. Cytogenetic analysis reveals several aberrations, including t(3;11), del(3)(p21), i(4p), i(8q), and additional translocations (t(17;?) and t(18;?)), along with a loss of one 21.- ONLINE INQUIRY
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