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TDG Knockout Cell Lysate

Product Name

TDG Knockout Cell Lysate

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Cat.No

ABC-KC2052

Species

Human

Size/Quantity

100ug

Shipping Info

Ice Pack

Storage

Store TDG KO Cell Lysate At -20℃. Please Avoid Repeated Freeze-Thaw Cycles.

Description

The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq, Jul 2008]

Stock

Custom

Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Host Cell

HeLa

Application

For research use only

Growth Conditions

37 ℃, 5% CO2

Growth Mode

Adherent

Product Type

CRISPR Knockout Cell Lysate

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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