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Transfected Stable Cell Lines

TNF-β Leeporter™ Luciferase Reporter-Raw264.7 Cell Line

  • For research use only

Cat No.

ABC-RC018Y
Product Type

Reporter Stable Cell Lines
Cell Type

Monocyte
Species

Mouse
Host Cell

Raw264.7
Source Organ

Blood / Macrophage
Disease

Leukemia
Storage

Liquid Nitrogen

TNF-β Leeporter™ Luciferase Reporter-Raw264.7 Cell Line is for high-sensitivity monitoring of lymphotoxin signaling in macrophage immunology studies.

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  • TNF-β Leeporter™ Luciferase Reporter-Raw264.7 Cell Line
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Home | Transfected Stable Cell Lines | TNF-β Leeporter™ Luciferase Reporter-Raw264.7 Cell Line

Description

TNF-β Leeporter™ Luciferase Reporter-Raw264.7 Cell Line is an advanced genetically engineered macrophage model derived from murine Raw264.7 cells, featuring a TNF-β (Tumor Necrosis Factor-beta) responsive luciferase reporter system with proprietary Leeporter™ technology. This innovative cell line maintains native macrophage characteristics including adherent morphology, phagocytic capability, and cytokine production while enabling ultrasensitive detection of TNF-β signaling activity. The Leeporter™ system provides exceptional luminescent signal amplification with minimal background noise, allowing precise quantification of TNF-β pathway activation for immunology research and drug discovery applications. Key macrophage surface markers (CD14, F4/80) remain intact, while the optimized reporter construct ensures accurate correlation between luminescence intensity and TNF-β signaling events. Cells are cryopreserved at low passage (<P20) to guarantee genetic stability and consistent performance. The cells have undergone rigorous quality control testing and are confirmed free of contamination from mycoplasma, fungi, yeast, and bacteria.

Species

Mouse
Cat.No

ABC-RC018Y
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Monocyte
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Blood / Macrophage
Disease

Leukemia
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Reporter Stable Cell Lines
Host Cell

Raw264.7
Gene Info

TNF-β / Leeporter / Luciferase
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • The TNF-β Leeporter™ Luciferase Reporter-Raw264.7 Cell Line is designed for sensitive monitoring of TNF-β promoter activity in macrophages. This stable reporter system quantifies lymphotoxin expression through luciferase activity driven by TNF-β regulatory elements, enabling detection of NFκB and inflammatory pathway activation. The cell line is optimized for studying lymphoid organogenesis, chronic inflammation mechanisms, and screening immunomodulatory compounds. With high signal sensitivity and rapid response characteristics, it provides a reliable platform for real-time assessment of TNF-β-mediated immune regulation in macrophage models.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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