For research use only
| Cat No. | ABC-TC534S |
| Product Type | Human Melanoma Cell Lines |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Skin |
| Disease | Melanotic Melanoma |
| Product Code | UACC 62; UACC.62; UACC62 |
UACC-62 melanoma cells harbor BRAF V600E mutation, express MART-1/S100, and serve as a model for melanoma biology and drug resistance research.
UACC-62 is a human melanoma cell line derived from the skin of a female patient with melanotic melanoma. These cells exhibit typical melanoma morphology, including polygonal shapes and prominent dendritic processes, and grow adherently in vitro. The cell line displays a near-triploid karyotype (modal 69; range 58–80) with characteristic chromosomal abnormalities associated with melanoma progression. It harbors mutated BRAF V600E and wild-type NRAS. UACC-62 expresses melanocyte lineage markers such as S100, HMB-45, MART-1, and Melan-A, confirming its melanocytic origin. UACC-62 also reflects genetic alterations common in melanoma, including mutations in key oncogenes, contributing to its aggressive phenotype and relevance for therapeutic screening.It exhibits high tumorigenicity and metastatic potential in immunocompromised mouse models, making it a valuable tool for studying melanoma biology, tumor invasion, and metastasis mechanisms, as well as serving as a representative model within skin cancer cell lines for drug discovery and comparative oncologic studies.
| Product Code | UACC 62; UACC.62; UACC62 |
| Species | Human |
| Cat.No | ABC-TC534S |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Skin |
| Disease | Melanotic Melanoma |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Melanoma Cell Lines |
| Key Features | – Backed by AcceGen advanced technology – Cryopreserved for highest viability and plating efficiency – Quality-guaranteed for accurate results – Timely technical support for best experimental outcomes |
| Quality Control | All cell lots test negative for HIV-1, HBV, HCV, mycoplasma, yeast, fungi, and other pathogens. |
UACC-62 cells are widely used in melanoma research for drug screening, signaling pathway analysis, and tumor metastasis studies. Their aggressive growth and metastatic traits provide a robust model to evaluate novel anti-melanoma compounds and explore molecular mechanisms underlying melanoma progression. These cells serve as an in vitro and in vivo platform for investigating tumor microenvironment interactions and resistance mechanisms to targeted therapies, supporting translational cancer research.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
The percentage of HMB-45 expression in UACC-62 Cell Line was detected by flow cytometry to be approximately 94.5%.
UACC-62 is a human melanoma cell line derived from metastatic melanoma. It is commonly used in cancer research to study melanoma biology, tumor progression, and drug response.
