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UACC-62

  • BSL

    1

  • 402
Tissue: Skin. 3N+/-, Near-triploid 69+/- (58-80).
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Home | Tumor Cell Lines | Human Tumor Cell Lines | UACC-62
Product Code

UACC 62; UACC.62; UACC62
Species

Human
Cat.No

ABC-TC534S
Quality Control

All cell lots test negative for HIV-1, HBV, HCV, mycoplasma, yeast, fungi, and other pathogens.
Product Category Tumor Cell Lines
Size/Quantity

1 vial
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Skin
Disease

Melanotic Melanoma
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Human Melanoma Cell Lines
Key Features

– Backed by AcceGen advanced technology

– Cryopreserved for highest viability and plating efficiency

– Quality-guaranteed for accurate results

– Timely technical support for best experimental outcomes

Description

UACC-62 is a human melanoma cell line derived from the skin of a female patient with melanotic melanoma. It grows adherently with polygonal, irregular morphology, prominent nucleoli, and malignant melanocyte features. UACC-62 has stable passage potential and is used at low to moderate passages. The karyotype is near-triploid (modal 69; range 58–80), indicating chromosomal instability. It harbors the BRAF V600E mutation and is NRAS wild-type. The cells express melanoma markers HMB-45, S100, and MART-1. These cells are widely used in drug screening, melanoma biology, and resistance research.
AcceGen Frozen Cells & Cell Lines 1 vial
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Citation

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Application

  • UACC-62 provides an ideal model for investigating the biological and molecular characteristics of human melanoma .This human tumor cell line is widely used to study melanoma-specific gene expression patterns and to develop novel anticancer therapies targeting melanoma..

  • Test Item
  • Flow Cytometry
  • Result

  • KY821 (no staining)

    UACC-62 (lgG ctrl)

    UACC-62 (full staining)

    Flow cytometry plot of KY821 (no staining), showing HMB-45 expression to be 0%.Flow cytometry plot of KY821 (no staining), showing HMB-45 expression to be 0%.Flow cytometry plot of UACC-62, showing HMB-45 expression to be 94.5%.

    The percentage of HMB-45 expression in UACC-62 Cell Line was detected by flow cytometry to be approximately 94.5%.

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