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USP18 Knockout Cell Lysate

Product Name

USP18 Knockout Cell Lysate

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Cat.No

ABC-KC2269

Species

Human

Size/Quantity

100ug

Shipping Info

Ice Pack

Storage

Store USP18 KO Cell Lysate At -20℃. Please Avoid Repeated Freeze-Thaw Cycles.

Description

The protein encoded by this gene belongs to the ubiquitin-specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates. It is highly expressed in liver and thymus, and is localized to the nucleus. This protein efficiently cleaves only ISG15 (a ubiquitin-like protein) fusions, and deletion of this gene in mice results in a massive increase of ISG15 conjugates in tissues, indicating that this protein is a major ISG15-specific protease. Mice lacking this gene are also hypersensitive to IFN, suggesting a function of this protein in downregulating IFN responses, independent of its isopeptidase activity towards ISG15. [provided by RefSeq, Sep 2011]

Stock

Custom

Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Host Cell

HeLa

Application

For research use only

Growth Conditions

37 ℃, 5% CO2

Growth Mode

Adherent

Product Type

CRISPR Knockout Cell Lysate

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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