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Transfected Stable Cell Lines

Xpress™ Dog GPRC5D Over-expressing Cell Line (293T)

  • For research use only

Cat No.

ABC-X0406C
Product Type

Overexpression Stable Cell Lines
Cell Type

Epithelial
Species

Dog
Host Cell

293T
Source Organ

Kidney
Disease

Normal
Storage

Liquid Nitrogen

293T cell line overexpressing canine GPRC5D, suitable for comparative immunology, CAR-T validation, and antibody discovery targeting GPRC5D.

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  • Xpress™ Dog GPRC5D Over-expressing Cell Line (293T)
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Dog GPRC5D Over-expressing Cell Line (293T)

Description

Dog GPRC5D 293T Overexpression Cell Line is a genetically engineered model derived from selected human embryonic kidney (293T) parental cell line based on customers’ requirement. Dog GPRC5D 293T overexpression cell line is generated by stable integration of exogenous dog GPRC5D into 293T host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
GPRC5D is an orphan G protein-coupled receptor (GPCR) involved in signal transduction pathways and has gained attention as a novel surface marker and therapeutic target, particularly in multiple myeloma. Its species-specific expression profile supports cross-species validation studies.
AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Dog
Cat.No

ABC-X0406C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Kidney
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

293T
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • This cell line offers a powerful tool for evaluating cross-reactivity and binding specificity of dog-targeted antibodies or therapeutics. It facilitates G protein-coupled receptor (GPCR) signaling research, antibody discovery, and translational immunotherapy development in canine models of disease.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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