For research use only
| Cat No. | ABC-X0123C |
| Product Type | Overexpression Stable Cell Lines |
| Cell Type | Epithelial |
| Species | Human |
| Host Cell | 293T |
| Source Organ | Kidney |
| Disease | Normal |
| Storage | Liquid Nitrogen |
The human CD48 overexpression cell line (293T) provides a stable model for immunological research, aiding in NK cell cytotoxicity and drug screenin.
Xpress™ Human CD48 over-expressing cell line (293T) is a stably modified model developed from 293T cells, expressing the human CD48 gene under the control of lentiviral vectors to ensure high and stable expression for immunological studies.
Target
CD48, a member of the signaling lymphocytic activation molecule (SLAM) family, is involved in T cell activation, adhesion, and NK cell-mediated cytotoxicity. It interacts with 2B4 (CD244) and has been linked to immune surveillance and cancer immune evasion.
| Species | Human |
| Cat.No | ABC-X0123C |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 °C, 5% CO₂ |
| Source Organ | Kidney |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Overexpression Stable Cell Lines |
| Host Cell | 293T |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
The Xpress™ Human CD48 over-expressing cell line (293T) provides a reliable model for functional assays involving NK cell cytotoxicity, immune checkpoint interactions, and drug screening targeting CD48-mediated signaling pathways.