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Xpress™ Human CD66e Over-expressing Cell Line (MC38)

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    1

  • 90
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human CD66e Over-expressing Cell Line (MC38)
Species

Human
Cat.No

ABC-X0140C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial-like
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Colon
Disease

Colon Adenocarcinoma
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

MC38

Description

Xpress™ Human CD66e over-expressing cell line (MC38) is a genetically engineered model derived from selected murine MC38 parental cell line based on customers’ requirement. Human CD66e overexpression cell line is generated by stable integration of exogenous human CD66e gene into MC38 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
CD66e (also known as CEACAM5 or CEA) is a cell adhesion molecule frequently overexpressed in colorectal, pancreatic, and lung cancers. It facilitates tumor growth, metastasis, and resistance to apoptosis, making it a prominent tumor-associated antigen for targeted therapies. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The Xpress™ Human CD66e over-expressing cell line (MC38) serves as a robust model for tumor antigen research, therapeutic antibody validation, and targeted drug screening. It supports development of CEACAM5-targeted approaches such as bispecific antibodies and CAR-T cells.

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