For research use only
| Cat No. | ABC-X0387C |
| Product Type | Overexpression Stable Cell Lines |
| Cell Type | Epithelial |
| Species | Human |
| Host Cell | CHOK1 |
| Source Organ | Ovary |
| Disease | Normal |
| Storage | Liquid Nitrogen |
Human CLDN2 stably expressed in CHOK1 cells, useful for tight junction biology, epithelial permeability, and studying claudin-mediated cancer mechanisms.
Xpress™ Human CLDN2 Overexpression Cell Line is a genetically engineered model derived from selected CHOK1 parental cell line based on customers’ requirement. CLDN2 overexpression cell line is generated by stable integration of exogenous human CLDN2 into CHOK1 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The CLDN2 gene encodes a tight junction protein crucial for paracellular permeability and epithelial barrier function. It is upregulated in several cancers and inflammatory diseases. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
| Species | Human |
| Cat.No | ABC-X0387C |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 °C, 5% CO2 |
| Source Organ | Ovary |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Overexpression Stable Cell Lines |
| Host Cell | CHOK1 |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
The CLDN2 CHOK1 Overexpression Cell Line enables investigation of epithelial barrier regulation, tight junction dynamics, and drug transport studies. It is applicable for cancer research, especially in gastrointestinal and renal pathophysiology.