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Xpress™ Human MTAP Over-expressing Cell Line (LU99)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human MTAP Over-expressing Cell Line (LU99)
Species

Human
Cat.No

ABC-X0391C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lung
Disease

Giant Cell Carcinoma
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

LU99

Description

Xpress™ Human MTAP Overexpression Cell Line is a genetically engineered model derived from selected LU99 parental cell line based on customers’ requirement. MTAP overexpression cell line is generated by stable integration of exogenous human MTAP into LU99 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The MTAP gene encodes methylthioadenosine phosphorylase, an enzyme involved in polyamine metabolism and methionine salvage. Loss of MTAP is common in cancer and associated with tumor progression. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The Human MTAP LU99 Overexpression Cell Line is used to study metabolic pathways in cancer, drug resistance, and potential metabolic vulnerabilities for targeted therapies.

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