Transfected Stable Cell Lines

Xpress™ Human MTAP Over-expressing Cell Line (LU99)

  • For research use only

Cat No.

ABC-X0391C

Product Type

Overexpression Stable Cell Lines

Cell Type

Epithelial

Species

Human

Host Cell

LU99

Source Organ

Lung

Disease

Giant Cell Carcinoma

Storage

Liquid Nitrogen

LU99 cells stably expressing human MTAP, applicable for research on purine salvage pathway, tumor suppressor roles, and MTAP-deficient cancer modeling.

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Description

Xpress™ Human MTAP Overexpression Cell Line is a genetically engineered model derived from selected LU99 parental cell line based on customers’ requirement. MTAP overexpression cell line is generated by stable integration of exogenous human MTAP into LU99 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The MTAP gene encodes methylthioadenosine phosphorylase, an enzyme involved in polyamine metabolism and methionine salvage. Loss of MTAP is common in cancer and associated with tumor progression. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human

Cat.No

ABC-X0391C

Product Category

Transfected Stable Cell Lines

Size/Quantity

1 vial

Cell Type

Epithelial

Growth Mode

Adherent

Shipping Info

Dry Ice

Growth Conditions

37 °C, 5% CO2

Source Organ

Lung

Disease

Giant Cell Carcinoma

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Overexpression Stable Cell Lines

Host Cell

LU99

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • The Human MTAP LU99 Overexpression Cell Line is used to study metabolic pathways in cancer, drug resistance, and potential metabolic vulnerabilities for targeted therapies.

Inquiring Xpress™ Human MTAP Over-expressing Cell Line (LU99)

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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