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Transfected Stable Cell Lines

Xpress™ Human PVRIG Over-expressing Cell Line (CHOK1)

  • For research use only

Cat No.

ABC-X0134C
Product Type

Overexpression Stable Cell Lines
Cell Type

Epithelial
Species

Human
Host Cell

CHOK1
Source Organ

Ovary
Disease

Normal
Storage

Liquid Nitrogen

The Human PVRIG Overexpression Cell Line based on CHOK1 cells supports immunotherapy research and aids in the in vitro characterization of the PVRIG-CD.

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  • Xpress™ Human PVRIG Over-expressing Cell Line (CHOK1)
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human PVRIG Over-expressing Cell Line (CHOK1)

Description

Xpress™ Human PVRIG over-expressing cell line is a genetically engineered model derived from selected CHOK1 parental cell line based on customers’ requirement. Human PVRIG overexpression cell line is generated by stable integration of exogenous human PVRIG into CHOK1 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
PVRIG (Poliovirus receptor-related immunoglobulin domain-containing) is an immune checkpoint receptor that binds to PVRL2 (CD112) and negatively regulates T cell activation. It is considered a novel immune inhibitory molecule contributing to immune escape in tumors. PVRIG expression has been noted in various cancers and is a target of emerging immunotherapies. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human
Cat.No

ABC-X0134C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Ovary
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

CHOK1
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • The PVRIG CHOK1 Overexpression Cell Line enables in vitro characterization of PVRIG-CD112 interactions and supports the screening of blocking antibodies or small molecules for immunotherapeutic strategies.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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