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Transfected Stable Cell Lines

Xpress™ Human RANKL Over-expressing Cell Line (CHOK1)

  • For research use only

Cat No.

ABC-X0241C
Product Type

Overexpression Stable Cell Lines
Cell Type

Epithelial
Species

Human
Host Cell

CHOK1
Source Organ

Ovary
Disease

Normal
Storage

Liquid Nitrogen

CHOK1 cell line overexpressing human RANKL, applicable for bone metabolism research, osteoclastogenesis assays, and signaling pathway studies.

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  • Xpress™ Human RANKL Over-expressing Cell Line (CHOK1)
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human RANKL Over-expressing Cell Line (CHOK1)

Description

This model was generated by integrating full-length human RANKL into the CHOK1 genome via lentiviral vectors. Stable expression was confirmed by qRT-PCR.
Target
RANKL (Receptor Activator of Nuclear Factor κB Ligand) is a key regulator of osteoclast differentiation and immune modulation. It is a therapeutic target in osteoporosis, rheumatoid arthritis, and cancer-induced bone disease. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human
Cat.No

ABC-X0241C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Ovary
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

CHOK1
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • This model is used for mechanistic studies of bone resorption, osteoimmunology, and development of anti-RANKL therapies such as denosumab.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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