+1 862-686-2696
Featured Products
Primary Cells
Immortalized Cell Lines
Stem Cells
Tumor Cell Lines
Transfected Stable Cell Lines
Exosomes
MicroRNA Agomir/Antagomir
Cell Culture Media, Kits & Reagents
Explore Products
Cell
Cell
MicroRNA
MicroRNA
Test and Analysis
Test and Analysis
Transfected Stable Cell Lines

Xpress™ Human SIRPA Over-expressing Cell Line (293T)

  • For research use only

Cat No.

ABC-X0194C
Product Type

Overexpression Stable Cell Lines
Cell Type

Epithelial
Species

Human
Host Cell

293T
Source Organ

Kidney
Disease

Normal
Storage

Liquid Nitrogen

The Xpress™ Human SIRPA Overexpression Cell Line (293T) is ideal for studying macrophage checkpoint signaling and CD47-SIRPa axis in cancer models.

Product Image
  • Xpress™ Human SIRPA Over-expressing Cell Line (293T)
Get a Quote
Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human SIRPA Over-expressing Cell Line (293T)

Description

Human SIRPA 293T Overexpression Cell Line is a genetically engineered model derived from selected human embryonic kidney 293T parental cell line based on customers’ requirement. SIRPA 293T overexpression cell line is generated by stable integration of exogenous human SIRPA into 293T host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT‑PCR.
Target
The SIRPA gene encodes signal regulatory protein α, an immunoglobulin superfamily receptor delivering inhibitory “don’t eat me” signals upon binding CD47. It modulates macrophage phagocytosis, dendritic‑cell activation, and antitumor immunity, with overexpression linked to tumor immune evasion and inflammatory disorders. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human
Cat.No

ABC-X0194C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Kidney
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

293T
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • The SIRPA 293T Overexpression Cell Line enables mechanistic studies of the CD47–SIRPA axis, assays of macrophage checkpoint blockade, and high‑throughput screening of anti‑CD47/SIRPA biologics or small‑molecule antagonists in human in‑vitro systems.

  • Online Inquiry
  • Product Reviews

Inquiring Xpress™ Human SIRPA Over-expressing Cell Line (293T)

We know how valuable your research is to you, but are you wondering what you can expect to pay for quick accurate results every time? Fill out a request in the form below and we’ll get back to you within 24 hours with a quote.
High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

Tags

Let's Advance Life Science Research Together

Contact Us
AcceGen Scroll Top Button